Hydrogen Therapies: An Overview

Hydrogen gas (H₂), recognized for its strong antioxidant properties, has become a growing focus of scientific and medical research. From laboratory studies to clinical trials, evidence is mounting that hydrogen could play a therapeutic role in a wide range of diseases.

Expanding research base:

• • A search for “hydrogen gas” in major medical databases reveals over 2,000 publications exploring its potential as a new drug substance.
  • Clinical trial registries show a surge in ongoing studies investigating hydrogen therapy across multiple medical fields.

Scope of this review:

• Examines findings from 81 clinical trials and 64 human studies on hydrogen therapy.
• Highlights positive indications in key disease areas such as:
  • Cardiovascular conditionsCancerRespiratory disordersCentral nervous system diseases

    Infectious diseases, and more

Challenges and innovation:

• Discusses existing administration methods
• Reviews emerging technologies designed to improve safety and delivery efficiency.

Key questions addressed:

• Could hydrogen gas become a new therapeutic agent in clinical practice?
• What forms of administration—inhalation, infusion, or others—might be most effective?
• For which medical indications might hydrogen therapy hold the greatest promise?